This Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce is pure comfort food magic. Tender bowtie pasta wraps around chunks of juicy Cajun-spiced chicken, all coated in a creamy, garlicky Alfredo sauce that’s as rich as it is indulgent. Each bite delivers a savory balance of smoky Cajun heat and cheesy goodness that keeps you coming back for more.

What makes this dish shine is its bold flavor combination and velvety texture. The Cajun seasoning brings a gentle kick, while the Alfredo sauce tames the spice with buttery, cheesy creaminess. Bowtie pasta, with its little ridges and pockets, catches all that delicious sauce so you taste every layer in every mouthful.

Why You’ll Love This Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce

This recipe transforms a weeknight dinner into something that tastes like it came from your favorite cozy restaurant. It’s easy enough for busy evenings but fancy enough for guests. Plus, it’s a one-pan wonder after the pasta’s cooked, so cleanup is minimal. The blend of garlic, cream, cheese, and Cajun spices is irresistible for anyone who loves a creamy pasta with personality.

What Kind of Cajun Seasoning Should I Use?

The Cajun seasoning is the heart of this dish, so choose a blend you love. Store-bought Cajun seasonings are quick and easy, but if you make your own, you can adjust the heat and salt to taste. Look for one with paprika, garlic powder, onion powder, oregano, thyme, and a hint of cayenne for the perfect balance of smokiness and spice.

Ingredients for the Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce

This pasta dish is all about bold flavors and creamy textures, so each ingredient plays an important role. Fresh chicken breasts bring hearty protein, while Cajun seasoning delivers smoky spice. The bowtie pasta catches every bit of sauce, and garlic infuses the Alfredo with irresistible aroma. Cream and cheese make the sauce luxuriously smooth.

Chicken breasts – Tender, lean protein that absorbs the Cajun flavors.
Bowtie pasta – Holds the creamy sauce beautifully in every fold.
Cajun seasoning – Adds spice, smokiness, and depth.
Garlic cloves – For rich, aromatic flavor in the Alfredo.
Heavy cream – Creates a silky, indulgent base for the sauce.
Parmesan cheese – Adds salty, nutty richness.
Mozzarella cheese – Gives the sauce gooey, cheesy texture.
Butter – Enhances creaminess and flavor.
Olive oil – Helps sear the chicken to golden perfection.
Salt and pepper – Balances and elevates all flavors.

How To Make the Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce

Step 1: Cook the Pasta

Bring a large pot of salted water to a boil. Cook the bowtie pasta according to the package instructions until al dente. Drain and set aside, reserving a small cup of pasta water.

Step 2: Season and Cook the Chicken

Pat the chicken breasts dry, then sprinkle generously with Cajun seasoning, salt, and pepper. Heat olive oil in a large skillet over medium-high heat. Sear the chicken for 5–6 minutes on each side until fully cooked. Remove from the skillet and slice into bite-sized pieces.

Step 3: Make the Garlic Alfredo Sauce

In the same skillet, lower the heat to medium and melt the butter. Add minced garlic and sauté for about 1 minute until fragrant. Pour in the heavy cream and stir, scraping up any browned bits from the chicken. Simmer for 3–4 minutes.

Step 4: Add the Cheese

Reduce the heat to low and stir in Parmesan and mozzarella cheeses until melted and smooth. Adjust seasoning with more Cajun spice, salt, or pepper if needed.

Step 5: Combine and Serve

Toss the cooked bowtie pasta and sliced chicken into the sauce, adding a splash of reserved pasta water if it needs loosening. Serve hot, garnished with extra Parmesan or parsley if desired.

Serving and Storing Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce

This hearty pasta recipe serves about 4 people generously, making it perfect for family dinners or an indulgent meal with friends. Serve it hot straight from the skillet so the cheese stays melty and the sauce remains silky. A sprinkle of extra Parmesan on top just before serving adds a finishing touch.

If you have leftovers, let the pasta cool to room temperature before transferring it to an airtight container. Store in the refrigerator for up to 3 days. To reheat, warm it gently in a skillet over low heat with a splash of milk or cream to revive the sauce’s creaminess.

What to Serve With Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce?

Garlic Bread

A classic choice to soak up every bit of creamy sauce.

Fresh Garden Salad

A crisp salad with mixed greens, cucumber, and a tangy vinaigrette balances the richness.

Roasted Asparagus

Lightly seasoned and oven-roasted asparagus brings a fresh, earthy flavor.

Steamed Broccoli

Bright and simple, steamed broccoli adds a healthy green to your plate.

Caprese Salad

Tomatoes, fresh mozzarella, and basil drizzled with balsamic glaze for a refreshing side.

Grilled Zucchini

Adds a smoky, savory bite without overpowering the pasta’s flavors.

Bruschetta

Toasted bread topped with fresh tomatoes, garlic, and herbs is a light, flavorful starter.

Want More Pasta Ideas?

If you love this Cheesy Garlic Cajun Chicken Bowtie Pasta in Alfredo Sauce, you’ll probably enjoy these other favorites:

• Creamy Beef and Shells Recipe for a rich, meaty comfort classic.
• One-Pot Smoked Sausage Pasta for a smoky, savory twist.
• Cheesesteak Tortellini in Rich Provolone Sauce for bold flavors in a creamy package.
• Creamy Ground Beef Alfredo Pasta when you crave indulgence in a single pot.
• Cheesy Baked Tortellini with Meat Sauce for oven-baked, cheesy perfection.

Save This Recipe For Later

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

And let me know in the comments how yours turned out. Did you kick up the Cajun spice or keep it mild? Did you add extra cheese for that gooey pull?

I love hearing how others make these recipes their own. Questions are welcome too — let’s help each other cook smarter.

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