Creamy Cajun Chicken Twisted Pasta with Mozzarella Alfredo

Save this recipe on:

There’s something wildly satisfying about the combination of spicy, creamy, and cheesy all wrapped up in a single comforting dish. This Creamy Cajun Chicken Twisted Pasta with Mozzarella Alfredo is where flavor meets indulgence, turning your average weeknight dinner into a dish everyone at the table will rave about. It’s a bold play on creamy pasta dishes, blending the heat of Cajun seasoning with a luxuriously smooth mozzarella Alfredo sauce.

Twisted pasta holds onto the rich sauce like a charm, while the Cajun-spiced chicken adds just enough kick to keep each bite exciting. This recipe is perfect for anyone looking to break out of a pasta rut and dive into something with a bit more personality. It’s quick enough for a weeknight meal but flavorful enough to impress guests.

Why You’ll Love This Creamy Cajun Chicken Twisted Pasta with Mozzarella Alfredo

This pasta is pure comfort with a fiery twist. The Cajun spices bring a warm depth without overpowering, and the mozzarella Alfredo sauce is creamy, smooth, and just the right amount of cheesy. The chicken is tender and savory, marinated to enhance every mouthful, and the twisted pasta ensures every bit of sauce clings to each bite. It’s a one-pan meal that looks gourmet but feels effortless to prepare.

Whether you’re cooking for picky eaters or spice lovers, this dish is versatile enough to please both. Plus, it reheats beautifully, making leftovers a next-day treat rather than a chore.

What Kind of Pasta Should I Use?

Twisted pasta like rotini or fusilli is ideal for this dish. Their shape is designed to catch and hold onto thick sauces, meaning every twist is loaded with flavor. If you can’t find twisted pasta, penne or rigatoni would work nicely too. Just avoid long, thin noodles like spaghetti—they don’t do this creamy Cajun Alfredo justice.

Ingredients for the Creamy Cajun Chicken Twisted Pasta with Mozzarella Alfredo

The beauty of this dish lies in the balance of spice, creaminess, and texture. Every ingredient plays a key role, so let’s highlight what you’ll need to bring this indulgent pasta to life.

• Twisted pasta (rotini or fusilli): Their spirals cling to the sauce, making every bite flavorful.
• Boneless skinless chicken breasts: These absorb the Cajun spice wonderfully and cook up juicy.
• Cajun seasoning: Adds a smoky, spicy kick that defines the character of the dish.
• Olive oil: Helps sear the chicken and infuses it with flavor.
• Garlic cloves: Minced for a punch of aromatic depth.
• Heavy cream: Forms the base of the rich Alfredo sauce.
• Mozzarella cheese: Melts into the sauce for that stretchy, creamy finish.
• Parmesan cheese: Adds a nutty sharpness to balance the creamy mozzarella.
• Butter: Adds richness and helps the sauce emulsify.
• Salt and black pepper: For seasoning the sauce and chicken to taste.
• Fresh parsley (optional): For a pop of color and fresh contrast.

How To Make the Creamy Cajun Chicken Twisted Pasta with Mozzarella Alfredo

Step 1: Cook the Pasta

Boil a large pot of salted water and cook the twisted pasta until al dente. Drain and set aside, reserving about a half cup of pasta water.

Step 2: Prepare the Chicken

Slice the chicken breasts into thin strips and season them with Cajun seasoning, salt, and pepper. In a large skillet over medium heat, add olive oil and sear the chicken until golden brown and cooked through. Remove and set aside.

Step 3: Build the Sauce

In the same skillet, melt butter and sauté the minced garlic until fragrant. Pour in the heavy cream, bringing it to a gentle simmer. Stir in shredded mozzarella and Parmesan until melted and smooth. Add salt and pepper to taste.

Step 4: Combine Everything

Add the cooked pasta and chicken into the sauce. If needed, use the reserved pasta water to loosen the sauce. Toss well until everything is fully coated and heated through.

Step 5: Serve It Up

Garnish with fresh parsley and extra Parmesan if you like. Serve hot and enjoy every creamy, spicy, cheesy forkful.

How to Serve and Store Creamy Cajun Chicken Twisted Pasta with Mozzarella Alfredo

This dish is best served piping hot, right out of the skillet. The cheese is melty, the sauce is silky, and the chicken is at peak tenderness. You can plate it individually or bring the whole skillet to the table for a more rustic, family-style approach.

It feeds about 4 hungry adults comfortably. If you’re planning to make it ahead, store the cooled pasta in an airtight container in the fridge for up to 3 days. When reheating, add a splash of milk or cream to loosen up the sauce and keep it creamy.

Avoid freezing, as the dairy-based sauce tends to separate when thawed.

What to Serve With Creamy Cajun Chicken Twisted Pasta?

Garlic Bread with Herbs

You can never go wrong with crusty garlic bread to scoop up that extra Alfredo sauce.

Classic Caesar Salad

A cool, crisp Caesar salad provides a refreshing contrast to the creamy, spicy pasta.

Roasted Broccoli

Roasting brings out a nutty flavor in the broccoli that pairs beautifully with Cajun seasoning.

Sautéed Green Beans

Lightly sautéed with a touch of lemon, they’re a bright sidekick to the richness of the dish.

Grilled Asparagus

Quickly grilled and sprinkled with a pinch of sea salt, asparagus adds a smoky green note.

Buttery Corn on the Cob

Sweet, juicy corn is a natural partner to spicy Cajun chicken and creamy Alfredo.

Tomato and Cucumber Salad

Tossed with vinegar and olive oil, it cuts through the richness and refreshes the palate.

Southern Sweet Tea or Lemonade

Finish the meal with a chilled, slightly sweet drink that mellows the spice.

Want More Pasta Ideas with a Kick?

If this Creamy Cajun Chicken Twisted Pasta with Mozzarella Alfredo stole your heart, then these bold, comforting pasta dishes might just become your next favorites:

• Try our Creamy Beef and Shells Recipe for a nostalgic, meaty twist.
• Dive into the hearty layers of flavor in Stovetop Creamy Ground Beef Pasta.
• For a touch of luxury, check out Cheesesteak Tortellini in Rich Provolone Sauce.
• Craving Alfredo with a twist? The Creamy Ground Beef Alfredo Pasta is your go-to.
• Don’t miss the smoky kick of the One Pot Smoked Sausage Pasta.

Save This Recipe For Later

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

And let me know in the comments how yours turned out. Did you dial up the Cajun seasoning or add some veggies? Maybe even swapped mozzarella for pepper jack?

I love hearing how others make these recipes their own. Questions are welcome too—let’s help each other make dinner a little more exciting.

Explore beautifully curated health-boosting drinks on Mia Recipes on Pinterest and discover your new go-to for feeling great!

Print

Save this recipe on: