Garlic Butter Shrimp Scampi Lasagna

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Creamy, garlicky, and packed with juicy shrimp in every bite, this Garlic Butter Shrimp Scampi Lasagna is where Italian comfort meets bold seafood flavor. Imagine layers of tender lasagna noodles, rich garlic butter sauce, perfectly cooked shrimp, and a medley of cheeses melted together into a golden, bubbly masterpiece.

This dish takes the familiar warmth of lasagna and infuses it with the luxurious brightness of shrimp scampi. It feels both indulgent and comforting, making it ideal for a cozy dinner at home or impressing guests at your next get-together. It’s a guaranteed crowd-pleaser that’s hard to resist from the very first forkful.

Why You’ll Love This Garlic Butter Shrimp Scampi Lasagna

You get the best of both worlds with this lasagna: rich, garlicky flavor from the scampi sauce, and cheesy, baked goodness from the traditional Italian dish. The garlic butter sauce soaks into each layer, making it irresistible. It also reheats beautifully, so leftovers are something to look forward to. Whether you’re a seafood lover or simply looking for a new twist on lasagna, this recipe delivers on flavor, texture, and satisfaction.

What Kind of Shrimp Should I Use?

For the best results, use large or extra-large shrimp that have been peeled and deveined. Fresh is great if you can find it, but high-quality frozen shrimp work beautifully too. If you’re using frozen, make sure to thaw them completely and pat dry before cooking to avoid excess moisture in your sauce. Wild-caught shrimp usually offer better flavor, and leaving the tails off makes eating much easier once baked into the lasagna.

Ingredients for the Garlic Butter Shrimp Scampi Lasagna

The ingredient list is short but strategic. Every component here plays a flavorful role in building up those luscious, garlicky, cheesy layers. Let’s talk about what you’ll need.

Lasagna noodles bring structure to the dish and create those classic layered bites that hold the sauce and shrimp perfectly.

Large shrimp are the star of the show. Their sweet, briny flavor soaks up the garlic butter and blends beautifully with the creamy layers.

Garlic is essential. You can’t have shrimp scampi without it. It adds sharpness and depth to the butter sauce.

Unsalted butter forms the rich, flavorful base of the scampi sauce and carries the garlic flavor throughout the lasagna.

Heavy cream gives the sauce its velvety texture, helping the cheese melt into something luxurious.

Parmesan cheese adds salty, nutty depth and helps thicken the sauce while baking into a golden, crispy topping.

Mozzarella cheese brings that stretchy, gooey texture every lasagna needs.

Lemon juice cuts through the richness and brightens the overall dish with a zesty pop.

Fresh parsley adds a final burst of color and freshness, keeping the dish from feeling too heavy.

How To Make the Garlic Butter Shrimp Scampi Lasagna

Step 1: Boil the Noodles

Cook the lasagna noodles until just al dente. You want them slightly firm since they’ll continue cooking in the oven. Drain and lay them flat on parchment to prevent sticking.

Step 2: Sauté the Shrimp

In a large skillet, melt some butter over medium heat. Add the garlic and shrimp, cooking until the shrimp are just pink. Remove the shrimp and set aside.

Step 3: Build the Scampi Sauce

In the same skillet, add more butter and garlic. Stir in the heavy cream and simmer until slightly thickened. Add lemon juice and a generous handful of Parmesan cheese. Stir until creamy and smooth.

Step 4: Assemble the Lasagna

In a greased baking dish, start layering noodles, scampi sauce, shrimp, mozzarella, and Parmesan. Repeat until you reach the top, finishing with sauce and extra cheese.

Step 5: Bake Until Golden

Cover with foil and bake at 375°F for 25 minutes. Then uncover and bake another 10-15 minutes until bubbly and golden on top.

Step 6: Rest and Serve

Let it rest for 10 minutes before slicing. Sprinkle chopped parsley over the top and serve warm.

How to Serve and Store Garlic Butter Shrimp Scampi Lasagna

This lasagna is best served warm, fresh out of the oven once it’s had time to settle for about 10 minutes. That little bit of resting helps the layers stay together when sliced and gives the flavors time to meld even more. Garnish with a sprinkle of fresh parsley and maybe an extra squeeze of lemon for brightness.

Leftovers can be stored in an airtight container in the fridge for up to 3 days. When reheating, cover with foil and warm it in a 350°F oven until heated through, or microwave in short intervals. It actually tastes even better the next day as the garlic and shrimp infuse into the cheese and noodles even more.

This recipe easily feeds 6 to 8 people depending on how generous your servings are.

What to Serve With Garlic Butter Shrimp Scampi Lasagna?

Classic Caesar Salad

The crisp romaine, tangy dressing, and crunchy croutons help balance the richness of the lasagna.

Garlic Bread or Baguette Slices

More garlic? Always. A crusty bread is perfect for soaking up extra sauce on the plate.

Roasted Asparagus

Simple and slightly charred, asparagus offers a fresh contrast to the creamy layers.

Lemon Butter Broccolini

This side dish echoes the lemony shrimp flavors and keeps everything light and bright.

White Wine (like Sauvignon Blanc)

If you’re serving this to guests, a chilled glass of white wine enhances the garlic and seafood notes beautifully.

Creamy Cucumber Salad

Cool and tangy cucumber salad with a bit of dill offers a refreshing palate cleanser between rich bites.

Steamed Green Beans

A touch of salt and a pat of butter is all you need. Green beans add a snap of color and a clean finish.

Want More Seafood Pasta Ideas?

If you’re into seafood pasta dishes that step beyond the ordinary, here are a few more recipes to add to your list:

• Creamy Ground Beef Alfredo Pasta has that same luscious creaminess with a hearty, meaty bite.
• One-Pot Smoked Sausage Pasta for something smoky, creamy, and easy to clean up.
• Cheesy Baked Tortellini with Meat Sauce when you’re craving cheesy comfort with minimal effort.
• Creamy Beef and Shells Recipe for a nostalgic, family-friendly meal.
• Cheesesteak Tortellini in Rich Provolone Sauce if you’re in the mood for a Philly-inspired twist.

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And let me know in the comments how yours turned out. Did you try a different cheese combo? Add scallops or spinach? I’d love to hear your spin on it!

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