Comfort food doesn’t get any more classic or satisfying than a slice of rich, juicy meatloaf. This Irresistible Pioneer Woman Meatloaf lives up to its name with bold flavor, a crave-worthy glaze, and the perfect tender texture that melts in your mouth. It’s hearty, homey, and fills your kitchen with that nostalgic smell that makes everyone excited to gather around the table.

This version adds a savory punch with pantry staples and a few little secrets to keep the meat moist and flavorful. Whether you’re planning a weeknight dinner or serving a crowd on Sunday evening, this meatloaf is always a hit. And the leftovers? Even better the next day on a sandwich or with eggs for brunch.

Why You’ll Love This Irresistible Pioneer Woman Meatloaf

This recipe checks every box for the ultimate comfort food: it’s simple, budget-friendly, and made with ingredients you likely already have on hand. The glaze is sticky and sweet with a kick of tang, while the meatloaf itself is full of savory depth. It holds its shape beautifully when sliced and never turns out dry, thanks to the mix of meats and a secret ingredient that locks in moisture.

Make it once and you’ll come back to it again and again, whether for family dinners, meal prep, or a cozy potluck dish everyone will ask you about.

What Kind of Ground Beef Should I Use?

A good meatloaf starts with good beef. Look for ground beef with an 80/20 ratio—that means 80% lean, 20% fat. This balance gives you enough fat for juicy texture without turning greasy. If you want to lighten things up, you can combine ground beef with ground pork or ground turkey for a different flavor twist. Just avoid using extra-lean meat by itself or you’ll lose that tender bite everyone loves in meatloaf.

Ingredients for the Irresistible Pioneer Woman Meatloaf

The ingredients for this meatloaf are humble but thoughtfully chosen. Each one plays a role in adding richness, moisture, and that nostalgic flavor that makes meatloaf so lovable.

Ground beef
Milk
Bread slices
Eggs
Grated Parmesan cheese
Salt and pepper
Seasoned salt
Minced parsley
Dry mustard
Ketchup
Brown sugar
Hot sauce (optional)

How To Make the Irresistible Pioneer Woman Meatloaf

Step 1: Prep the Soaking Bread

Tear the bread slices into small pieces and soak them in milk in a large mixing bowl. Let them sit for a few minutes until the bread is fully softened. This step adds moisture to your meatloaf.

Step 2: Add the Beef and Seasonings

Add the ground beef to the soaked bread, followed by eggs, grated Parmesan, salt, pepper, seasoned salt, dry mustard, and minced parsley. Mix everything together gently using your hands or a spoon until just combined.

Step 3: Shape and Bake

Form the mixture into a loaf shape and place it on a lined baking sheet or loaf pan. Bake at 350°F for about 45 minutes.

Step 4: Glaze Time

In a small bowl, mix together ketchup, brown sugar, and a dash of hot sauce if using. After 45 minutes of baking, spoon the glaze generously over the top of the meatloaf and return it to the oven for another 15-20 minutes until the glaze is set and slightly caramelized.

Step 5: Rest and Slice

Let the meatloaf rest for 10 minutes before slicing. This helps keep all those tasty juices inside.

How to Serve and Store Irresistible Pioneer Woman Meatloaf

This meatloaf feeds about 6 people comfortably, depending on portion size. It’s a perfect main dish for family dinners and easy to double for a bigger group.

Leftovers can be stored in the fridge for up to 4 days and freeze beautifully for up to 2 months. Simply reheat slices in the oven or microwave and enjoy that same hearty flavor all over again.

For something different, try slicing it cold and layering it into a sandwich with a swipe of mayo and crisp lettuce—a comfort food lover’s dream.